Essential Biochemistry - Enzymes (Section 1 - No. 33)

What would be the effect of a non-competitive inhibitor on a Lineweaver-Burk plot?

The y-intercept changes and the x-intercept remains the same.

The x-intercept changes and the y-intercept remains the same.

Both the x and y intercepts change.

Neither intercept changes.

Noncompetitive inhibitors alter the Vmax, hence the y-intercept will change, while the Km, and therefore the x-intercept, will remain the same.